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Portail > Offres > Offre UPR2301-TANSAG-001 - Catalyse duale : fonctionnalisation regiosélective de liaisons C(sp3)-H non-activées (Ingénieur de recherche H/F en synthèse chimique)

Dual catalysis: regioselective functionalization of unbiased C(sp3)-H bonds (Research engineer in chemical synthesis)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : jeudi 14 juillet 2022

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General information

Reference : UPR2301-TANSAG-001
Workplace : GIF SUR YVETTE
Date of publication : Thursday, June 23, 2022
Type of Contract : FTC Technical / Administrative
Contract Period : 13 months
Expected date of employment : 1 December 2022
Proportion of work : Full time
Remuneration : between 2536€ and 2720€ gross monthly depending on experience
Desired level of education : PhD
Experience required : Indifferent


The objective of this project is to develop dual catalytic systems for the regioselective C-H functionalization of linear alkanes. The envisaged approach requires the synthesis and development of new bifunctional photocatalysts able to perform Hydrogen Atom Transfer (HAT) under light irradiation. The regioselectivity will result from a supramolecular assembly between the photocatalyst and the substrate. These photocatalysts will then be used in synergy with an organometallic catalyst to engage the radical intermediates generated by HAT in cross-coupling reactions with aryl or alkyl halides.
The synthesis of the photocatalysts will be carried out at ICSN under the supervision of Dr. Tanguy Saget. Afterwards, these photocatalysts will be tested at CEA-Saclay in the HTE (High-Throughput Experiment) unit directed by Dr. Eugénie Romero. This technology will greatly facilitate the discovery and optimization of efficient dual catalytic systems.


- Organic synthesis and development of catalytic methods.
- Select appropriate synthesis techniques; develop experimental protocols
- Validate data and interpret results
- Coordinate and perform routine characterization of prepared products
- Disseminate and valorize the results
- To get information about the potential risks related to the laboratory techniques and chemical products


- Strong background in organic and organometallic chemistry
- Experience in catalysis
- Mastery of classical analytical techniques in organic synthesis (TLC, NMR, HRMS, IR...)
- Use of bibliographic research tools (mastery)
- Work independently, with a sense of adaptability and creativity
- Work in a team on a collaborative project, and in a multicultural environment
- Respect for health and safety rules
- Ability to listen

Work Context

The recruited agent will be hosted at the Institute of Chemistry of Natural Substances (ICSN). The ICSN is a CNRS Research Unit whose research areas are chemistry and biology. It is part of the Université Paris-Saclay which groups together the research and teaching establishments of the south of Paris since 2015. The ICSN is located on the campus of Gif-sur-Yvette and has about 125 employees, including 60 permanent staff spread over 3 buildings. Within the "Organic Synthesis and Catalytic Methods" department, the recruited agent will join the "Organometallic Catalysis and Functional Molecule Synthesis" team, which consists of 2 researchers and 3 CDD/doctoral students. He/she will be placed under the hierarchical authority of the team leader. The agent will work in direct link with the team leader, as well as in collaboration with the other members of the team. The project will be carried out in collaboration with Eugénie Romero's HTE unit within the SCBM team at CEA-Saclay. Occasional stays in CEA-Saclay laboratories, located near the ICSN, will be made during the project.

Constraints and risks

Potential risks inherent to research work in the field of chemistry.

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