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Portail > Offres > Offre UMR8197-NATBOI-092 - Chercheur H/F en neurophysiologie

Postdoctoral position in neurophysiology

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mardi 14 décembre 2021

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General information

Reference : UMR8197-NATBOI-092
Workplace : PARIS 05
Date of publication : Tuesday, November 23, 2021
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 April 2022
Proportion of work : Full time
Remuneration : between 2800 and 3800 € monthly gross salary according to experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

The candidate's main mission will be to carry a series of experiments combining chronic electrophysiological and behavioral measurements on freely moving rodents, optogenetic perturbations of the activity of specific neuronal circuits and neuroanatomical tracings. He or she will also be involved in analyzing the data, writing scientific papers, managing a reasonable share of lab tasks and contributing to the team's scientific life through discussions and presentations.

Activities

The candidate's main activity will be to conduct experiments aiming at understanding how the cerebellum influences the coupling between the vestibular system and forebrain representations of head direction in space. Anatomical tracings and perturbations of cerebellar activity combined with electrophysiological recordings will be used to probe and identify the cerebellar modules influencing the thalamic representation of head direction. Electrophysiological recordings and perturbation of the activity of these modules combined with behavioral measurements will be used to understand their role in the coding of head direction in space. This activity will also include data analysis and the writing of scientific papers.

Skills

The expected skills are, by order of priority: some experience with surgical procedures on rodents for performing intracranial implantation and/or injection, some experience with chronic electrophysiological measurements in rodents, some experience with animal handling and behavioral testing and finally some experience with common histological procedures (slicing and staining). An additional experience in programming in R and/or Python would be appreciated. The ability and motivation to work in a collaborative environment and to precisely document key experimental procedures are also important.

Work Context

The Institut de biologie de l'ENS (IBENS) is a center focused on fundamental research in various areas of biology. It is a joint ENS-CNRS-INSERM research unit, gathering more than 300 staff members dispatched in 30 independent teams. Research projects are highly collaborative and multidisciplinary and often combine experimental and theoretical approaches. Research at the IBENS spans a large spectrum of biological disciplines: neurosciences, developmental biology, functional genomics or ecology and evolution.

Several technical platforms are available in imaging, genomics, proteomics, bioinformatics and instrumentation. Research at the IBENS benefits from a resourceful and rich academic environment comprising other ENS scientific departments (physics, chemistry, cognitive sciences, mathematics and informatics) and nearby research institutes. The IBENS is actively involved in teaching at the Bsc and MSc levels and in training young researchers.

The host team (Neurophysiology of Brain Circuits), headed by Clément Léna et Daniela Popa, gathers 12 members including 3 permanent researchers, 2 postdoctoral fellows and 7 doctoral candidates. The team's main scientific goal is to understand the nature of the interactions between the cerebellum and a series of forebrain structures in the context of motor, cognitive and emotional functions and in normal vs pathological conditions.

The candidate will work under the direct supervision of Guillaume Dugué, permanent researcher in the team.

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