Reference : UMR7592-NICBOR-002
Workplace : PARIS 13
Date of publication : Thursday, May 12, 2022
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 December 2022
Proportion of work : Full time
Remuneration : from 2700€ gross depending on experience
Desired level of education : PhD
Experience required : Indifferent
A post-doctoral position is open in the team "Mechanotransduction: from the cell surface to the nucleus" at the Institut Jacques Monod (UMR7592 CNRS/Université Paris Cité, Paris, France - www.ijm.fr/en/860/equipes/mecanotransduction.htm) to work on a project that aims to reveal how the nucleus of epithelial cells perceives mechanical forces and adapts its functions to them. This project is part of the team's general interest in understanding how macromolecular complexes transmit and transform mechanical signals within and between cells, and how these signals affect cellular functions such as adhesion, migration, proliferation and transcriptional activity. To do so, the team applies and develops genetically encoded tools, quantitative fluorescence microscopy and micromanipulation approaches to monitor and measure molecular functions in living cells.
The successful candidate will :
- participate in the design of the project,
- use and develop new methodologies,
- carry out the experiments,
- analyze and communicate the results,
- write reports and research papers.
The candidate will use a wide range of approaches including advanced live cell microscopy (FRET, FLIM, FCS), cell biology (mammalian cell culture, transfection, molecular biology...) and cell and tissue micromanipulation.
The candidate must hold a PhD (or have obtained it before the beginning of the contract), in biology or soft matter physics with a strong interest in biology. The candidate must be able to work independently but also in a team in the framework of a collaborative project with teams outside the institute, have the ability to lead a project, and must be able to express himself/herself in English, written and spoken (French is not mandatory).
The Institut Jacques Monod (IJM), housed in a 1800 square meter building, located on the new campus of the urban project Paris rive gauche, is one of the main centers for basic research in biology in Paris, and offers a multidisciplinary research environment. The IJM brings together some thirty research groups working on cell and developmental biology, biophysics and genomics. The postdoctoral researcher will benefit from a highly stimulating scientific environment, and will have access to state-of-the-art equipment (notably the photonic microscopy, electron microscopy and flow cytometry platform), located at the IJM.
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