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Portal > Offres > Offre UMR7289-THOBRO-002 - (H/F) Neuroprotection de l'ischémie cérebrale chez le primate non-humain

(M/F) Neuroprotection of transient cerebral ischemia in non human primates

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR7289-THOBRO-002
Workplace : MARSEILLE 05
Date of publication : Thursday, October 03, 2019
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 2 December 2019
Proportion of work : Full time
Remuneration : Gross salary between 2695€ and 3107€ per month depending on the experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

The project combines behavioral and functional explorations using MRI, electrophysiology and histology to characterize the consequences of transient cerebral ischemia. It will evaluate the structural and functional consequences of neuroprotection by comparing one group of animals receiving no treatment with one group of animals exposed to neuroprotection in the per-ischemic period.

Activities

- Training and evaluation of macaque monkeys in various behavioural tasks.
- Analysis of MRI images to quantify the lesion volumes.
- Electrophysiological data analysis to evaluate the post-ischemic plasticity of descending motor pathways.
- Post-mortem histological analysis

Skills

Abilities in the following areas are desirable:
a) experimental or translational neuroscience research interests in brain injury or stroke
b) experience in behavioral/clinical evaluation of lab animals
c) hands-on experience in working with NHPs
d) training in brain imaging and/or in-vivo electrophysiology.
Experience with programming is required for data analysis (Matlab, Python). The successful applicant will be working in an international research institute, therefore proficiency in English is necessary.

Work Context

The project will be performed at the Timone Neuroscience Institute (INT) in Marseille (http://www.int.univ-amu.fr/) that is part of the CNRS and Aix-Marseille Université. This institute carries out world class research in fundamental neurosciences, from cellular to cognitive levels. It bridges levels of organization of the nervous system within a functional approach to understand the neural underpinnings of our behaviour and of their dysfunctions in neurological and psychiatric diseases. The candidate will work in the "Cognitive Motor Control" team directed by Dr Thomas Brochier in close collaboration with the Critical Care Unit at the Timone Hospital (Pr Velly) and the INT MRI center.

Additional Information

Qualified candidates should submit curriculum vitae, a statement of research experience and interests and names and contact information for three references.

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