Reference : UMR7210-VALEMI-008
Workplace : PARIS 12
Date of publication : Wednesday, May 11, 2022
Type of Contract : FTC Technical / Administrative
Contract Period : 24 months
Expected date of employment : 1 September 2022
Proportion of work : Full time
Remuneration : between 2690 et 2890 €brus per month depending on experience
Desired level of education : Engineer
Experience required : Indifferent
Responsible for the management of a microscopy platform for two-photon imaging and photo-stimulation and for the maintenance and optimization of the optical microscopes of the group.
Design all or part of an optical microscope
-Management of the microscopy platform (planning of access to the platform; adaptation of the microscope to the needs of the users; maintenance and adjustment of the microscope .
-Technological monitoring of the team's instrumentation and lasers.
Follow-up of the practicals for thematic schools (e.g. the annual school of optogenetics (CNRS training company).
-Consult with suppliers to guide the choice of materials and processes, negotiate costs and deadlines, prepare purchase calls.
We are looking for a motivated candidate with a PhD in physics or an engineering degree, with the following skills:
- proven experience in imaging and optical microscopy
- ability to synthesize and write scientific documents
- strong motivation to work in an interdisciplinary environment (physical-biological)
- good knowledge of the English language
The Institut de la Vision is an interdisciplinary research center affiliated with Sorbonne University, and supported by INSERM and CNRS. It is located on the campus of the Centre Hospitalier National d'Ophtalmologie des XV-XX (CHNO des XV-XX). It was created in 2008 by Pr Sahel, the current director, in order to bridge academic, private and clinical research. It is organized into 5 departments and 18 research teams.
The institute has facilities for cell culture and purified neuron cultures. It also has a molecular biology facility for the design, purification and production of viruses. It is equipped with a stereotactic injection facility for the injection of AAV into the retina and brain of mice and an animal facility.
Emiliani's team has 8 state-of-the-art optical microscopes, including 3 systems for in vitro photoactivation and 2P-holographic electrophysiology, 2 systems for in vivo holography/imaging and 2 holographic endoscopes for 2P imaging and photoactivation in freely moving animals. They have also recently received funding to set up a biphotonic microscopy platform for optogenetic imaging and photo-stimulation in collaboration with the company 3i and a new optical microscope for in vivo 2P and 3P imaging and photo-stimulation (funding: ERC Advanced grant).
The group is also equipped with an electromechanical workshop including a 3D printer for the manufacturing of small microscope elements.
Constraints and risks
Standard risks of working in a laser experiment room.
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