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Portail > Offres > Offre UMR5558-FABVAV-001 - Chercheur post-doctorant (H/F) pour l'analyse fonctionnelle de la co-adaptation dans les interactions hôte-microbiote chez les insectes

Post-doctoral position (H/F) for the functional analysis of co-adaptation in host-microbiota interac

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR5558-FABVAV-001
Workplace : VILLEURBANNE
Date of publication : Tuesday, February 05, 2019
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 April 2019
Proportion of work : Full time
Remuneration : Between 2052 and 2370 euros depending on experience
Desired level of education : Higher than 5-year university degree
Experience required : Indifferent

Missions

The objectives of the ANR project "Host-Microbiota co-adaptations: mechanisms and consequences", are to decipher if, and if yes how, host and their microbiota (HxM) are co-adapted, using as models interactions between hemipteran insects and their symbiotic bacteria. The originality of the project resides in that we will undertake these analyses in a comparative framework by studying natural H×M interactions, but also neo H×M interactions that will be tested both immediately after the breaking down of potential co-adaptations, and after experimental co-evolution. In this frame, transcriptomic data will be generated on both hosts and symbionts simultaneously. The mission is to analyse this dataset in order to determine the mechanisms underlying co-adaptations in these systems.

Activities

- Processing of raw data and quantification of gene expression
- Determination of differentially expressed genes
- Functional bioinformatic analysis of these genes
- Analysis of polymorphism evolution during the experimental evolution
- Integration of these results with phenotypic and physiological data

Skills

- Expert knowledge in bioinformatics applied to genomics and transcriptomics
- Expert knowledge on the evolution and functionning of symbiotic systems
- Experience on arthropod symbiosis
- Deep knowledge in English
- Aptitude for team work and networking

Work Context

The recruited person will work within the "Genetics and evolution of host-parasite interactions" team of the Laboratory of Biometry - Evolutionary Biology, UMR 5558 of the CNRS and the University Claude Bernard Lyon I whose research is organized around two unifying themes: "Biometrics" and "Evolutionary Biology". This specificity has presided over the creation of the laboratory and gives it its originality. The scientific results of the LBBE are born in the synergy of the methodological points of view, whose core is the mathematical as well as the statistical and computerized modeling, and of the evolutionary perspectives which organizes the researches independently of the level of biological organization. The position being part of an ANR project, there will be strong interactions with the other partners of the project (Institute of genetics, environment and plant protection in Rennes and Laboratory Functional biology, insects and interaction in Lyon).

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