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Portail > Offres > Offre UMR5309-AMITOU-002 - Chercheur (H/F) en Biologie de la reproduction

RESEARCHER IN THE FIELD OF REPRODUCTIVE BIOLOGY

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mardi 11 octobre 2022

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General information

Reference : UMR5309-AMITOU-002
Workplace : LA TRONCHE
Date of publication : Tuesday, September 20, 2022
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 January 2023
Proportion of work : Full time
Remuneration : Between 2805,35€ and 3224,81€ bruts per month depending of the experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

The project is part of a research program in the field of mammalian reproductive biology. The researcher will take charge of the metabolic and functional analysis of human and murine spermatozoa in physiological and pathophysiological contexts.

Activities

The project aims at: i.) Characterizing at the functional and molecular level, the metabolic pathways of energy production in human and murine spermatozoa, ii.) Characterizing the metabolic status of spermatozoa from infertile patients and pathologic mutant mouse models, iii.) developing innovative therapeutic strategies for male infertility.
Most of the work will take place at the Institut pour l'Avancée des Biosciences (IAB, Grenoble). The researcher will rely on the skills in spermatogenesis and sperm physiology of the team directed by Dr Aminata Touré (DR2, CNRS) and on the skills in metabolism of the collaborating team directed by Dr Carina Prip-Buus (DR2, CNRS. Institute Cochin, Paris). The researcher will also rely on services provided by external platforms specializing in metabolism, lipidomics and proteomics.

Skills

- Knowledge in Energy metabolism
- Knowledge in Reproductive biology: spermatogenesis, sperm physiology
- Knowledge in Bioinformatics
- Technical expertise in molecular and cellular biology, biochemistry
- Expertise in animal experimentation (rodents)
- Ability to work independently
- Communication skills
- Collaborative work and team spirit.

Work Context

The Institute for Advanced Biosciences (IAB) is a mixed research unit supervised by the CNRS (UMR 5309), INSERM (U1209) and the University of Grenoble Alpes. The IAB is developing a set of fundamental and translational research programs in the fields of epigenetics, environment, cell plasticity with application to cancers, parasitic infections and infertility. The IAB comprises 19 teams and 5 technical platforms.
The researcher will work within the research group 'Physiology and physiopathology of Sperm cells', which comprises: a full time Research Director (DR2 CNRS), a researcher (CRCN Inserm), a Lecturer (MCF UGA), a PhD student and Master students.

Websites:
Institut pour l'Avancée des Biosciences, Grenoble : https://iab.univ-grenoble-alpes.fr/l-institut
Dr A. Touré : https://tourelab.fr/
Institut Cochin, Paris : https://institutcochin.fr/
Dr C. Prip-Buus : https://institutcochin.fr/projets-recherche/metabolisme-lipidique-mitochondrie-maladies-metaboliques

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