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Reference : UMR5286-DAVBER-001
Workplace : LYON 08
Date of publication : Friday, December 21, 2018
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 April 2019
Proportion of work : Full time
Remuneration : about 2500 euros gross monthly
Desired level of education : PhD
Experience required : Indifferent
The postdoctoral researcher will be part of the Senescence escape mechanisms laboratory headed by David Bernard. He/she will develop a project investigating the role of new mechanisms controlling cellular senescence (in the context of Ca2+ fluxes, Ca2+ buffering and ER-mitochondria contact points) and its impact on tumor initiation and aging (previous work of the team in that topic: Wiel et al, Nat Comm, 2014; Warnier et al, Aging Cell, 2018; Ma et al, Aging Cell, 2018; Martin & Bernard, Cell Calcium, 2018). He/she will work under the supervision of David Bernard and in collaboration with other team members within the framework a French National Cancer Institute (INCA) supported project.
The postdoctoral fellow will be in charge of developing the above-mentioned project. He/she shall handle design, plan, perform and interpret various experiments. He/she should master the associated literature. He/she should be able to communicate his/her results in the lab and outside. He/she should be able to work independently as well as with other team members and collaborators pending of the project needs.
We are looking for a highly motivated and dynamic scientist. The applicant must hold a doctorate in the field of molecular and cellular biology with good knowledge of cellular senescence and/or cancer/aging biology. Experience in cell culture, manipulating gene expression as well as in classical cell and molecular biology techniques is required. Experience in Ca2+ field, confocal microscopy or in handling mice will be a plus. Applicant should be a fist author of at least one publication related to the subject or skills required for the project. Candidates must have a positive attitude as a team member and should be able to communicate (oral and written skills) in English.
Our laboratory is composed of between 10-15 people and we are working in a dynamic and international environment. The candidate will also benefit from the scientific environment (24 teams and about 450 people dedicated to cancer research) and technical platforms provided by the CRCL.
Constraints and risks
Work with normal/primary human cells and potentially with mice.
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