Post doctoral candidate (M/F) (18 months) Compartmentalization and organization of ELF3 in plant adaptation to temperature (COOL-PLANT)

Job Description

Missions

A postdoctoral position for 18 months is available in the StrucDev team at the Laboratoire de Physiologie Cellulaire et Végétale (LPCV, Grenoble) as part of the ANR-funded project COOL-PLANT. The project will investigate the role and composition of biomolecular condensates formed by the transcriptional regulator EARLY FLOWERING 3 (ELF3) in plant temperature sensing. Specifically, the project aims to understand how liquid–liquid phase separation (LLPS) of ELF3, the composition of its condensates, and their dynamic transition from liquid to low-mobility or hydrogel states regulate transcriptional responses to temperature changes.

Activity

The postdoctoral researcher will identify and characterize the molecular composition of ELF3-driven condensates under different temperature conditions in vivo and investigate how interacting proteins and environmental factors influence their behavior. Using a combination of genetics, advanced microscopy and biophysics, the project will examine the composition, physical properties and dynamics of ELF3 assemblies in response to temperature shifts and client proteins. The goal is to establish a mechanistic framework linking the different molecular states of ELF3—monomeric, multimeric and condensed—to plant temperature-dependent growth responses.

Your Profil

Skills

Applicants should hold a PhD in plant biology, biochemistry, biophysics, molecular biology or a related field. Strong experience in plant biology, protein biochemistry and microscopy is required, with expertise in at least one of the following areas: plant genetics, advanced fluorescence microscopy, or protein phase separation/biophysics. Experience with protein purification, in vitro reconstitution, quantitative imaging and different labelling technics will be highly valued. Candidates should demonstrate strong analytical and communication skills, the ability to work independently while collaborating in an interdisciplinary environment, and motivation to address fundamental questions in plant environmental sensing. Fluency in written and spoken English is required; knowledge of French is desirable. Good interpersonal skills and the ability to work both independently and as part of an international team are essential.

Your Work Environment

The researcher will be employed by the CNRS and will join the StrucDev team under the lead of Chloe Zubieta at the Laboratory of Plant and Cell Physiology (LPCV, UMR 5168 – CNRS, CEA, Université Grenoble Alpes, INRAE) in Grenoble, France. The project will be supervised by Stephanie Hutin. The team investigates the atomic and molecular determinants of protein function in plant development and how environmental conditions influence the structure and activity of transcription factors, transcriptional and translational regulators, and scaffold proteins.

Constraints and risks

no

Compensation and benefits

Compensation

3041 et 4292 €gross monthly salary depending on experience, in accordance with the current CNRS salary scale

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

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