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Reference : UMR5168-GIOFIN-004
Workplace : GRENOBLE
Date of publication : Thursday, July 8, 2021
Type of Contract : FTC Technical / Administrative
Contract Period : 24 months
Expected date of employment : 1 October 2021
Proportion of work : Full time
Remuneration : 2000-2500 euros monthly depending on experience
Desired level of education : 5-year university degree
Experience required : Indifferent
The selected candidate will participate in the development of a multidisciplinary project aimed at exploring the structural basis of acclimation in marine phytoplankton.
- Contribute to the image acquisition process using focused ion beam scanning electron microscopes
- Develop an image analysis protocol allowing to switch from a semi-automatic to an automatic segmentation mode
- Test the possibility of introducing an artificial intelligence approach in the automatic segmentation process, using a database of 58 tomograms fully reconstructed and manually verified to train the neural network.
- experience in image processing/segmentation
- Python programming
- knowledge in biology
- experience in artificial intelligence is a plus
The candidate will join the team "Light, Photosynthesis and Metabolism" (http://lpm-research.com/), which is composed of about 15 people and which is interested in the bioenergetic processes of microorganisms through a multidisciplinary approach.
The selected candidate will work in close collaboration with the team leader (Giovanni Finazzi) in the framework of an ERC funding; He/she will work in close collaboration with the electron microscopy and imaging teams of the Institute of Structural Biology (Guy Schoehn, Leandro Estrozi) and of the Institute of Interdisciplinary Research of CEAGrenoble (Pierre-Henri Jouneau)
The host team is part of the Laboratory of Cellular and Plant Physiology (LPCV), which is a joint research unit CNRS-University Grenoble Alpes-CEA-INRA composed of about 100 collaborators, located at the CEA on the Scientific Polygon in Grenoble.
Photosynthesis, an essential biological process on our planet, has enabled colonization on land and sea by plants and phytoplankton, respectively. Research is now focused on elucidating this process in phytoplankton. From an energetic point of view, a microalgae is a "vehicle" containing mitochondria (a combustion engine using carbon to produce energy and CO2) and chloroplasts (a solar panel using light to produce energy and O2). Using cellular or subcellular imaging approaches, the EU-funded ChloroMito project will examine the hypothesis that the photosynthetic efficiency of oceanic microalgae is caused by the close connection between their solar panel and combustion engine. The research will provide a better understanding of how subcellular energy interactions optimize photosynthesis in marine phytoplankton.
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