En poursuivant votre navigation sur ce site, vous acceptez le dépôt de cookies dans votre navigateur. (En savoir plus)
Portail > Offres > Offre UMR5070-CAMLIB-020 - Ingénieur de recherche en modélisation du vivant (H/F)

Research Engineer in Life Modeling (M / F)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mercredi 12 mai 2021

Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler. Les informations de votre profil complètent celles associées à chaque candidature. Afin d’augmenter votre visibilité sur notre Portail Emploi et ainsi permettre aux recruteurs de consulter votre profil candidat, vous avez la possibilité de déposer votre CV dans notre CVThèque en un clic !

Faites connaître cette offre !

General information

Reference : UMR5070-CAMLIB-020
Workplace : TOULOUSE
Date of publication : Wednesday, April 21, 2021
Type of Contract : FTC Technical / Administrative
Contract Period : 14 months
Expected date of employment : 1 July 2021
Proportion of work : Full time
Remuneration : Between 2437 and 2616 euros gross monthly according to experience
Desired level of education : Higher than 5-year university degree
Experience required : 1 to 4 years

Missions

• Upgrade an agent-based model of interaction between CTL and cancer cell
• Develop tools for design and optimization of experimental protocols
• Analyze experimental validation data

Activities

We are looking for an engineer in life modeling who will work under the supervision of Dr. Sylvain Cussat-Blanc. He/she will be hosted at the RESTORE institute, Toulouse, France. The objective of this interdisciplinary project is to develop (1) an automatic calibration tool and (2) tools for the design and optimization of experimental protocols for a T cell/target cell interaction model already calibrated on melanoma cells and cytotoxic T cells [Kazhen et al. 2019, Scientific Report]. The aim is to be able to indivualize an agent-oriented model using data from patient samples and/or new cell types. To this end, statistical indicators will have to be proposed in order to evaluate both the quality of experimental data and the results of simulations. Once calibrated, the simulation platform should be usable by biologists to develop and optimize new experimental protocols and evaluate their results via the model.

Skills

We are looking for a talented candidate with a PhD degree in Computer Science to work in a multidisciplinary research environment. Experience in modeling biological systems is required, preferably with a good knowledge of cancer. The candidate should be creative, highly motivated and have good skills in writing scientific publications.

Work Context

The candidate will be assigned to the RESTORE institute, a service and research unit of 100 people, in the SiliCell research team, under the responsibility of Sylvain Cussat-Blanc.

The project will be carried out in close collaboration with Dr Salvatore Valittuti (CRCT INSERM U1037), immunologist and pathologist, expert in immunological synapses. The candidate will work with a post-doctoral fellow in immunology who will generate experimental data to calibrate and/or validate the model throughout its development process.

Constraints and risks

None

We talk about it on Twitter!